Miniaturized Electronic Circuit Design Challenges for Ingestible Devices

The gastro-intestinal (GI) tract is a very important part of the human digestive system but remains largely inaccessible for unobtrusive monitoring. Ingestible electronic devices are a very interesting concept to address this need. This paper discusses the current state of ingestible electronic devices and explores the potential they hold to provide unprecedented insight by measuring several aspects of the complex bio-chemical processes that happen in the GI tract in real-time. This will require novel sensor technology capable of measuring relevant markers with adequate specificity and accuracy. In order to be able to scale this functionality down to a form factor of an easily digestible pill, ultra-low-power wireless interface electronics are needed. This poses certain challenges and innovation opportunities related to sensing, wireless communication and powering to enable the next generation of ingestible electronic devices. [2020-0164]