Adaptation upon Ozone Exposure in Mice and Rats

Abstract Changes In the activity of the enzymes creatine kinase and glucose-6-phosphate dehydrogenase observed In blood plasma and alveolar macrophages (AH) respectively, as well as changes In AH adherence caused by 0 3 concentrations of 40 Mg/ 1 5 and higher reveal activation of this pulmonary defense system after 0, exposure. Such an activation creates a certain threshold. If the defence can fully cope with an offending Irritant the state of adaptation may have been reached.