Androgenic Effects on Ventricular Repolarization: A Translational Study From the International Pharmacovigilance Database to iPSC-Cardiomyocytes

Joe Elie Salem,Tao Yang,Javid Moslehi,Xavier Waintraub,Estelle Gandjbakhch,Anne Bachelot,Françoise Hidden-Lucet,Jean-Sébastien Hulot,Björn C. Knollmann,B. Lebrun-Vignes,Christian Funck-Brentano,Andrew M. Glazer,Dan M. Roden

Androgenic Effects on Ventricular Repolarization: A Translational Study From the International Pharmacovigilance Database to iPSC-Cardiomyocytes

2019

Joe Elie Salem
Tao Yang
Javid Moslehi
Xavier Waintraub
Estelle Gandjbakhch
Anne Bachelot
Françoise Hidden-Lucet
Jean-Sébastien Hulot
Björn C. Knollmann
B. Lebrun-Vignes
Christian Funck-Brentano
Andrew M. Glazer
Dan M. Roden

Background: Male hypogonadism, arising from a range of etiologies including androgen-deprivation therapies (ADTs), has been reported as a risk factor for acquired long-QT syndrome (aLQTS) and torsa...

Keywords:

Cardiology
Acquired long QT syndrome
Internal medicine
Pharmacovigilance
Diabetes mellitus
Androgen Antagonists
Ventricular Repolarization
Medicine

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