TSLP Polymorphisms are Associated with Asthma in a Sex-Specific Fashion

Gary M. Hunninghake,Manuel Soto-Quiros,Lydiana Avila,Hong P. Kim,Jessica Lasky-Su,Nicholas Rafaels,Ingo Ruczinski,T.H. Beaty,Rasika A. Mathias,Kathleen C. Barnes,Jemma B. Wilk,George T. O′Connor,W. James Gauderman,Hita Vora,James W. Baurley,Frank D. Gilliland,Catherine Liang,Jody S. Sylvia,Barbara J. Klanderman,Sunita Sharma,Blanca E. Himes,Cara Bossley,Elliot Israel,Benjamin A. Raby,Andrew Bush,Augustine M. K. Choi,Scott T. Weiss,Juan C. Celedón

TSLP Polymorphisms are Associated with Asthma in a Sex-Specific Fashion

2010

Background Single nucleotide polymorphisms (SNPs) in thymic stromal lymphopoietin (TSLP) have been associated with IgE (in girls) and asthma (in general). We sought to determine whether TSLP SNPs are associated with asthma in a sex-specific fashion.

Keywords:

Immunology
Immunoglobulin E
Genotype
Genome-wide association study
Single-nucleotide polymorphism
Asthma
Thymic stromal lymphopoietin
Medicine
Polymorphism (computer science)
Immunopathology
Genetic association

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