Quinazolines and 1,4-benzodiazepines. Part XXXVIII. The reaction of hydrazines with 6-chloro-2-chloromethyl-4-phenylquinazoline 3-oxide

The reactions of hydrazines with 6-chloro-2-chloromethyl-4-phenylquinazoline 3-oxide have been investigated. In the case of hydrazine, a benzodiazepine was obtained, and some of its reactions with acetylating agents are discussed. When 1,1-dimethylhydrazine and methylhydrazine were used, quinazoline hydrazones were obtained. A mechanism is suggested.