Excel Diet for Homocystinuria: How Can We Use?

Background: Methionine restricted diet prevents homocystinuria complications, seems like Marfan syndrome. Homocystinuria is a metabolism disease but Marfan syndrome is a genetic disorder have similar symptoms. But only homocystinuria have neuropsycologic abnormalities and high methionine levels. Homocystein is an intermediate oxidized product, transform both of methionine or cystein. High methionine levels lead to neuropsycologic features, may be also premature ageing, in marfanoid persons with homocystinuria, because of creates over-methylating status in whole organism and also DNA. These high methylating status have found in cancer patients.