Periorificial Granulomatous Dermatitis

Periorificial granulomatous dermatitis (PGD) was first reported in 1970 in the French literature by Gianotti et al. [1]. Gianotti et al. [1] described five Italian children ranging in age from 2.5 to 7 years with a distinctive eruption of monomorphous papules around the mouth with a granulomatous pattern noted histologically. In 1974, Marten et al. [2] reported 22 Black children with a similar eruption limited to the face. In 1989, Frieden et al. [3] termed this disease granulomatous perioral dermatitis in children. In 1990, Williams et al. [4] reported 5 very similar patients and coined the term facial Afro-Caribbean childhood eruption (FACE) to reflect that all their cases occurred in Afro-Caribbean children. In 1996, Knautz et al. [5] suggested the term childhood granulomatous periorificial dermatitis for this eruption to point out the frequent perinasal or periocular involvement and to avoid the term FACE which limits the diagnosis to Afro-Caribbeans.