FLOATING DRUG DELIVERY SYSTEM: A NOVEL ACCEPTABLE APPROACH

The aim of writing this review on gastroretentive drug delivery systems was to compile the recent literature with special focus on various gastroretentive approaches that have recently become leading methodologies in the field of site-specific orally administered controlled/Sustained release drug delivery. Several approaches are currently utilized in the prolongation of the GRT, including floating drug delivery systems (FDDS), swelling and expanding systems, polymeric bioadhesive systems, high-density systems, modified-shape systems and other delayed gastric emptying devices. In this review, current & recent developments of Stomach Specific floating drug delivery systems are discussed. This review also summarizes the in vitro techniques, in vivo studies to evaluate the performance and application of floating systems. These systems are useful to several problems encountered during the development of a pharmaceutical dosage form.