UNCLASSIFIED RHABDOMYOSARCOMA IN A PATIENT WITH ANTI-HU SYNDROME
2005
Anti-Hu syndrome is a paraneoplastic neurological syndrome, most frequently associated with small cell carcinoma of the lung. Subacute sensory neuronopathy is thought to be the most frequent presentation of the anti-Hu syndrome, but it seems that sensory-motor neu- ropathy is the most common form in the anti-Hu neu- ropathy. Neurological symptoms often appear before the associated cancer has been identifi ed. Sometimes the tumor is discovered months or even a few years af- ter the appearance of the neurological syndrome. FDG- PET scan seems a better method for fi nding the tumor in patients with paraneoplastic neurological syndrome and anti-Hu antibodies who had negative test results after an initial workup using radiological methods. In this case report we present a patient with the anti- Hu syndrome associated with an unclassifi ed rhab- domyosarcoma with epitheloid cellular morphology and neuroendocrine differentiation. ABBREVIATIONS:
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