Volumetric properties of amino acids in aqueous d-mannitol solutions at 298.15 K

Abstract The densities of solutions of glycine, l -alanine, l -serine and l -threonine in water and in aqueous solutions of d -mannitol were measured with an Anton Paar Model 55 densimeter at 298.15 K. The apparent molar volumes, limiting partial molar volumes, transfer partial molar volumes, and hydration numbers have been determined for the amino acids. The above parameters are used to interpret the solute–solute and solute–solvent interactions of amino acids in aqueous d -mannitol solution. Substituent effects are also discussed.