Two cases of granular cell ameloblastoma

Granular cell ameloblastoma is a variant form of ameloblastoma characterized by extensive granular cell changes of tumor cells histologically. The incidence of this tumor is relatively low.Case 1: A 69-year-old woman presented with swelling of the right side of the mandible, which had persisted for 3 years. On radiography, a honeycomb radiolucent lesion with an ill-defined margin was noted from the canine to the second molar on the right side of the mandible. We performed segmental resection of the mandible and reconstruction with an iliac bone graft. The parenchyma showed a plexiform and follicular pattern, with large tumor nests in some areas. Bone marrow invasion was noted.Case 2: A 57-year-old woman presented with swelling and pain in the molar region at the right side of the mandible. Symptoms had persisted for 10 years. On radiography, a cystic radiolucent lesion with a well defined margin, extending from first molar to the ascending ramus on the right side of the mandible was observed. We enucleated the tumor along with the surrounding bone. A plexiform pattern was noted adjacent to the cystic cavity along with a thick connective tissue capsule.