Electrochemical sensing of anti-inflammatory agent in paramedical sample based on FeMoSe2 modified SPCE: Comparison of various preparation methods and morphological effects

Abstract We demonstrate the different types of synthesis processes (hydrothermal, microwave and simple chemical synthesis) to prepare the Fe doped molybdenum diselenides (H-FeMoSe 2 , M-FeMoSe 2 , and C-FeMoSe 2 ) and investigate their relevant electrocatalytic activities. The Fe doped MoSe 2 exhibited an enhanced charge transfer conductivity and electrocatalytic activity. Especially, the H-FeMoSe 2 with vertically aligned structures facilitate the abundant exposed active edge sites. Thus, H-FeMoSe 2 modified screen-printed carbon electrode (H-FeMoSe 2 /SPCE) exhibited the lower R ct and better active surface area than that of M-FeMoSe 2 /SPCE and C-FeMoSe 2 /SPCE. As well as, the electrochemical sensing of mesalamine (MES) at H-FeMoSe 2 /SPCE is comparatively 0.46 and 1.28 fold higher than that obtained at M-FeMoSe 2 /SPCE and C-FeMoSe 2 /SPCE respectively. Thus, H-FeMoSe 2 /SPCE was concluded as an excellent electrocatalyst for sensing of MES and performed DPV technique. As the results, very low detection limit (0.8 nM) of MES was achieved at H-FeMoSe 2 /SPCE. Hence, the selected H-FeMoSe 2 /SPCE was successfully subjected to the real-time detection of MES by using a paramedical tablet and reported the excellent recovery range.