No Causal Link between Phosphodiesterase Type 5 Inhibition and Melanoma

Jenny Z. Wang,Stephanie Le,Claire Alexanian,Sucharita Boddu,Alexander A. Merleev,Alina I. Marusina,Emanual Maverakis

No Causal Link between Phosphodiesterase Type 5 Inhibition and Melanoma

2018

Jenny Z. Wang
Stephanie Le
Claire Alexanian
Sucharita Boddu
Alexander A. Merleev
Alina I. Marusina
Emanual Maverakis

Purpose To examine the association between phosphodiesterase type 5 (PDE5) inhibitor use and melanoma by 1) conducting a systematic review of observational studies; and 2) determining if low PDE5A gene expression in human melanoma correlated with decreased overall survival.

Keywords:

Melanoma
VARDENAFIL DIHYDROCHLORIDE
cGMP-specific phosphodiesterase type 5
Tadalafil
Pharmacology
Medicine
Confounding
PDE5A Gene
Internal medicine
Cochrane Library
Observational study
Oncology
Cyclic guanosine monophosphate

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