Therapeutic Considerations in an 8-Year-old Girl with Clear Cell Adenocarcinoma of the Cervix

ABSTRACT Invasive clear cell adenocarcinoma in the adult is difficult to manage, and in the pediatric population, it presents extremely challenging therapeutic considerations, including decreased long-term morbidity for patients who, when cured, have life expectancies measured in decades. Consequently, less mutilating surgery, improved functional and cosmetic results, and desired future fertility of the patient must be considered. This case report discusses invasive clear cell adenocarcinoma of the cervix in an 8-year-old girl not exposed prenatally to diethylstilbestrol and the unique considerations in therapeutic management. (J GYNECOL SURG 13:31, 1997)