In-hospital Mortality after Liver Transplantation due to COVID-19.

This case report describes the clinical course and management of a 49-year male, with end-stage liver disease secondary to nonB/non-C cirrhosis, no comorbids, and MELD score of 28, underwent LT in May 2020. His pre-transplant course was complicated by ICU admissions due to portosystemic encephalopathy, ememesis, ascites, and sepsis. He underwent three subsequent weekly COVID-19 PCR tests prior to the transplant, which were reported negative. The operative and postoperative course of was smooth until developed shortness of breath on the 11th postoperative day (POD) and died at POD 27. The patient received low dose immunosuppression including steroids, antibiotics, etc. broad spectrum, antifungal and enoxaparin. positive post-transplant PCR and chest CT for COVID-19 pneumonia. His D-dimer, C-RP and ferritin were persistently raised. Throughout the post-transplant course, his liver function tests remained within normal range and he had no systemic signs of infection. Regarding the source of COVID-19, one of the family members tested positive for COVID-19 PCR and was in close contact with the patient before he was admitted for transplantation.