Relationship between dietary patterns and non alcoholic fatty liver disease among Karamay adults

Objective To explore the relationship between dietary patterns and non alcoholic fatty liver disease (NAFLD) in Karamay adults. Methods A total of 2377 subjects aged 20-75 years old who took health check-up during April and June 2011 were included in this investigation.Body mass index (BMI), waist to hip ratio (WHR), systolic blood pressure (SBP), diastolic blood pressure (DBP), triglyceride (TG), total cholesterol (TC), aspartate aminotransferase (AST) and serum uric acid (SUA) were measured.Food intake patterns and life style of the participants were accessed by using food frequency questionnaire (FFQ). Main component analysis and multivariate logistic regression model were used to explore the association of dietary patterns with NAFLD. Results Five dietary patterns were identified, including "condiment dietary pattern" , "western dietary pattern" , "conventional healthy dietary pattern" , "snacks and bean pattern" , and "high protein dietary pattern". Subjects of "condiment dietary pattern" , "western dietary pattern" or "conventional healthy dietary pattern" showed significantly different prevalence of NAFLD (χ2 values were 149.873, 8.247 and 18.766, respectively; all P<0.05). In condiment dietary pattern, age, BMI, WHR, SUA and TG were significantly different in Q4 group (F values were 8.42, 5.64, 12.78, 10.72 and 9.63, respectively; all P<0.05). For those with western dietary pattern, age, WHR, SBP, SUA, TC and TG showed significant different trend (F values were 9.84, 6.87, 6.11, 10.61, 6.87 and 8.13, respectively; all P<0.05). However, subjects with conventional healthy dietary pattern showed a significant different trend of age, BMI, WHR, SBP, SUA and AST (F values were 19.13, 11.09, 13.89, 6.11, 15.12, 6.19, respectively; all P<0.05). After age, BMI, WHR, SBP, SUA, AST, TC and TG were adjusted, the risk of NAFLD of those with "condiment pattern" or "western pattern" were significantly increased (odds ratio (OR) were 1.33 (95% confidence interval (CI) 0.95-1.87) and 1.36 (95% CI 0.979-1.902), respectively). Conclusion Dietary pattern may be associated with NAFLD.People need to learn healthy dietary habit to prevent NAFLD. Key words: Fatty liver; Diet Surveys; Risk factors