Provocarea trombofiliei: profilul pacientelor cu trombofilii compuse rare

Thrombophilia is a multigenic disorder. Factor V Leiden mu­ta­tion and protein gene G20210A mutation are the most com­mon inherited thrombophilias. Individuals who are ho­mo­zy­gous have a higher risk of thrombosis compared to those who are heterozygous. Inherited thrombophilia is as­so­cia­ted with a predisposition to venous – not arterial – throm­bo­embolism. Pregnancy increases the risk of de­ve­lo­ping venous thromboembolism. The aim of this study is to find the link between inherited thrombophilia (compound ho­mo­zy­gous polymorphisms) and obstetric pathology in preg­nant women.