A Comparative Study of the Immunotropic and Hepatotropic Action of Beekeeping Products in Rats with Drug-Induced Hepatitis

The experiments on white rats with CCl4-induced hepatitis showed the ability of lyophilized drone larvae (LDL) preparations to normalize (restore at the level of intact animals) the parameters of phagocytosis (PhAL, PPhc, PhIL) and the levels of lysozyme and total bilirubin, to increase (in comparison to the control) the biological activity of blood serum and the β-lysine level, and to reduce the activity of alanine aminotransferase and alkaline phosphatase. Simultaneously, LDL decreases the level of cholesterol and triglycerides in the liver tissue and increases the content of glycogen. The commercial preparations apilac and Liv-52 are less effective: some of the above parameters remain at the control level.