Autonomic symptoms in idiopathic Parkinson’s disease

Abstract Aim. Autonomic symptoms (AS) are one of the major causes affecting quality of life in Parkinson’s disease (PD) patients and contribute to the disease burden. Our aim is to investigate the occurence of AS and to evaluate the relation between AS and the demographic and clinical features of PD patients. Method. In this study 66 idiopathic PD patients (47 men) were evaluated for the presence of AS during the last month with the SCOPA-AUT (Scales for Outcomes in Parkinson’s Disease; SCOPA) questionnaire, which consists of 23 items in six domains: gastrointestinal (7), urinary (6), cardiovascular (3), thermoregulatory (4), pupillomotor (1), and sexual (2). The maximum score is 69, with a score range per item from 0 (never experiencing the symptom) to 3 (often experiencing the symptom). Associations between AS and duration of disease, age onset of disease, treatment and Hoehn Y I-IV) idi. Total SKOPA-AUT skoru 15,9 idi. Total skor ile yas ve cinsiyet arasinda bir iliski olmayip (p>0,05), hastalik suresi ve evresi arasinda anlamli bir iliski bulundu (p<0,05). OS’larin en fazla gozlendigi alan gastrointestinal sistem olup hastalik suresi ve siddeti ile de iliskili oldugu saptandi. Sonuc. PH’nin erken evrelerinde ve hatta hastaligin baslangic donemlerinde dahi OS’lar gorulebilmekte ve hastalik siddeti ve suresi ile de artis gostermektedir. Parkinson hastalarinda OS’lara yonelik ileri tetkik ve tedavinin planlanmasi, hastalarin hayat kalitesini arttiracaktir. Anahtar sozcukler: Parkinson hastaligi, SCOPA-AUT, otonomik semptomlar