Recurrent Anemia in Himachal Pradesh Females: Deficiency of Vitamin B12 and Folic Acid

A comparative study was designed to find out the cause of recurrent anemia in Himachal Pradesh females. 138 blood samples were collected from several area of Himachal pradesh, The study has been divided into four groups, C-1 (30 Healthy Control, age 0-14 years), C-2 (37 Healthy control, age 15-45 years), T-1(32 Subjects, age 0-14 years), T-2 (39 subjects, age 15-45 years) . In all study groups Hemoglobin, Vitamin B12, Folic acid, Homocysteine and 5-methyl THF were analyzed. A significant decrease in Vitamin B12 and folate levels in both the test groups as compared to control groups was observed whereas a significant increase in the level of Homocysteine and 5-MTHF (5 methy tetrahydrofolate) was observed in both the test groups as compared to control groups. It is concluded that folic acid affects the anemia symptoms of vitamin B12 deficiency. Vitamin B12 deficiency may be one of the prominent reason for recurrent anemia in Himachal Pradesh females.