Analysis of clinical influential factors among preterm infants in NICU

Objective:To analyze thestrains' types caused the infections of preterminfants inneonatal intensive care unit (NICU),to learn the clinical manifestations of bacterial infection and explore therelevant factor of the infections,so provide references for the clinicalprevention and therapy of preterminfants' infection.Methods:76 cases of infection were chosen from 325 preterm infants admitted by our hospital from May 2008 to May 2010.Several items were investigated in the retrospective study,such as clinical manifestation,laboratory examinations,spectral analysisof thebacteria and curative effects.80 cases of normal preterm infantswere chosen as control group,and the logistic regression were employed to screen the predisposing factors.Results:Gram-negative bacteria (80.6%) had caused the majority infections of preterm infants,and klebsiella pneumonia was the prevalent component.The early infection presentations include apnea,feeding intolerance,abnormal temperature,and delayed jaundice,et al.Predisposing factors in preterminfantsare mechanical ventilation,intravenous nutrition,weight,gestational age,premature rupture of membranes.Conclusion:Varieties of clinical manifestations are involved in the infections of preterminfants,because some lack of representativeness,so we should pay close attention.We should use the antibiotic reasonablin the course of therapy,and preventive treatment can be provided if the infants own several predisposing factors for infection.