An Experimental Study Of Ginsenosides On The Treatment Of Spinal Cord Injure In Rats

Objective To investigate the protective effects of Ginsenosides on experimentally secondary injured spinal cord in rats.Methods eighty rats were randomly divided into four groups:sham operation group,SCI group,GS treatment group,and MP treatment group.Rats in sham operation group had only laminectomy performed and no spinal cord injury;rats in other three groups were injured at the level of T11 spinal segment of the rats by Allen's weight drop method.The functional tests were performed at day 1、7 and 14.All injured rats were killed on the 14 day and the injured spinal cords were taken out for histological tests.Results The function of the spinal cord of rats in varying degrees to resume.In The functional tests,Rats in the GS and MP groups gained more significant rehabilitation than those in the control grnup(P0.05),while no significant difference was observed between the two groups(P0.05).It was revealed by pathological analysis is that in the GS and MP groups,Secondary injuries were less than the control group at the same points.Conclusion GS has some protective effects on spinal cord in rats.