Recognizing the Origin of Ventricular Premature Depolarization During Sinus Rhythm and During Non-sustained Tachycardia

Premature ventricular complexes (PVCs) are common and usually benign. Occasionally, intervention may be required. In these cases, localization of the origin of the PVCs or non-sustained ventricular tachycardia (NSVT) may be important in guiding therapy. A brief review is undertaken of the various methods which can be utilized to determine the site of origin of the PVCs/NSVT, ranging from the simple electrocardiogram to electrophysiological techniques to complex three-dimensional mapping systems. Case vignettes are provided to illustrate patients in whom therapy may be beneficial.