The value of Cone-Beam CT-guided Radiofrequency Ablation in the treatment of pulmonary malignancies(≤ 3 cm)

The aim of this study is to explore the safety and efficacy of Cone-Beam computed tomography (CBCT) guided radiofrequency ablation (RFA) in the treatment of pulmonary malignancies. 31 patients with pulmonary malignant tumors (≤ 3 cmin diameter) were enrolled to this study. Total 43 CBCT guided RFA treatments were performed, including 7 patients undergoing multiple treatments. The target tumor puncture success rate, tumor remission rate, postoperative cumulative survival rate, tumor-free survival rate and complication rate were analyzed. All 43 CBCT guided RFA procedures successfully punctured the target tumors. Complications included 5 cases of pneumothorax and 3 cases of hemoptysis. For the 31 patients who underwent CBCT guided RFA, the 1-year and 2-year cumulative survival rates were 80.6% and 54.8% respectively.The 1-year and 2-year disease-free survival rates were 54.8% and 32.3% respectively.The 1, 3 and 6-month remission rates were 78.4%, 68.7% and 63.3% respectively. The average cumulative radiation dose and average effective radiation dose were 194.62 ± 105.51 mGy and 5.41 ± 3.45 mSv, respectively. CBCT help to shorten the operation time, reduce the unnecessary interventions and also reduce the incidence of complications.CBCT guided RFA is one safe and efficacious treatment for pulmonary malignancies.