Outcomes of hypertensive obstetric patients in the Maltese Islands

a Chinese population with the highest rate of MTHFR C677T mutation. The number of cases is rather low in the NTD group, as in the control group, and larger population studies are needed to confirm this association. These results suggest that the presence of MTHFR C677T in mothers with normal folate levels may be a risk factor for NTD development in our population and that consideration should perhaps be given to folate supplementation.