Application of Combined Antifungal Agents in the Leather Industry

Dimethyl fumarate(B),propyl-p-hydroxybenzoate(C),cinnamic acid(D),isothiozolone(E) and sample A(A) which was synthesized by ourselves,and their eight combinations-A∶E=10∶7,A∶E=5∶10,B∶E=10∶8,B∶E=5∶10,C∶E=10∶6,C∶E=6∶10,(E+B)∶A=10∶5(E∶B=5∶5) and(E+C)∶A=10∶5(E∶C=5∶5)-were used on antifungal treatment of wet blue and finished leather.The antifungal activity of treated leathers was determined by the method of antibacterial circle.Results showed that only E could be used on wet blue and finished leather to control the growth of moulds.For the antifungal activity of E is much better than that of A,B,C and D.Used on the wet blue and finished leather,the eight combined antifungal agents showed similar antifungal activity to E,and their antifungal effects were much better than that of single A,B,C and D.