Synthesis of lactivicin and its derivatives

Hideaki Natsugari,Yasuhiko Kawano,Akira Morimoto,Kouichi Yoshioka,Michihiko Ochiai

Synthesis of lactivicin and its derivatives

1987

Hideaki Natsugari
Yasuhiko Kawano
Akira Morimoto
Kouichi Yoshioka
Michihiko Ochiai

Lactivicin, a new type of antibiotic having β-lactam-like activity, and its derivatives were synthesized starting from 4-benzyloxycarbonylamino-3-isoxazolidinones and 2-oxoglutaric acid.

Keywords:

Lactivicin
Chemistry
Lactone
Biological activity
Organic chemistry
Biochemistry
antibacterial agent

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