Penile Plication in Peyronie’s Disease: Technique Evolution and Recent Advances

Penile plication is an important option when considering the surgical management of Peyronie’s disease (PD). In this review, we discuss the evolution and recent advances in the use of penile plication to treat PD. Recent studies have demonstrated the successful application of penile plication to severe PD, which is often managed with more invasive procedures. Penile plication has been successfully combined with excision procedures to address severe forms of PD. In addition, a non-degloving approach was shown to be a safe, non-inferior alternative to degloving in penile plication. New plication techniques have addressed common postoperative complaints such as palpable knots and penile shortening. Updated recommendations to reduce the need for surgical revision were published. Data on long-term patient and partner sexual satisfaction was reported. Finally, the cost-effectiveness of plication was compared to other treatment options. Penile plication remains an important, cost-effective option for the treatment of PD. Recent data shows that penile plication can be used in complex PD cases, and with recent technique refinements, it can be performed with a minimally invasive approach to decrease associated complications.