Biosensing of Neurotoxicity to Prevent Bioterrorist Threats and Harmful Algal Blooms

The chapter discusses the different types of amperometric sensors based on the inhibition of butyrylcholinesterase for the analysis of neurotoxins. Analytical characteristics of sensors based on the manganese dioxide allow determining the neurotoxins in the nanomolar concentration range. The authors of this publication examined in detail the application of such sensors for monitoring of water samples. The data obtained indicates the presence of anatoxin A(s) in the analyzed samples. The study revealed the potential of the developed sensors to monitor the neurotoxic cyanobacteria at water “blooms”.