MP30-09 PROSPECTIVELY ASSIGNED POSITIVE CONTRAST ENHANCEMENT SCORE DETECTS MORE CLINICALLY SIGNIFICANT PROSTATE CANCER IN MULTIPARAMETRIC MAGNETIC RESONANCE IMAGING USING PI-RADS V2

INTRODUCTION AND OBJECTIVES:The standard multiparametric MRI (mpMRI) of the prostate includes dynamic contrast-enhanced (DCE), T2- and diffusion-weighted (DWI) imaging. DCE affects PI-RADS v2 score only in a small group of lesions in the peripheral zone (PZ) with DWI score of 3. Emerging data suggest comparable diagnostic performance of biparametric (bp) vs. mpMRI, the former forgoing DCE. Potential advantages of bpMRI include reduced cost, no need for a venous access and reduced risk of contrast-related side effects. However, the value of DCE for lesions other than PZ lesions with a DWI score of 3 is currently unknown. This study aims to assess the impact of DCE status for discrimination of clinically significant PCa in lesions for which the current scoring approach is not influenced by DCE findings (i.e., all but PZ lesions with a DWI score of 3).METHODS:This single-center, retrospective study of prospectively collected data included all men with abnormal 3T mpMRI examinations (PIRADS v2 score ≥3), with...