[Progeria syndrome--case report].

: A girl with progeria is described. The main clinical characteristics of this syndrome, also known as the Hutchinson-Gillford Disease are: alopecia, thin skin, loss of subcutaneous fat tissue, delayed eruption of deciduous and permanent dentition, skeletal hypoplasia, dysplasia and degeneration, retarded growth, preserved intellectual abilities, The main pathohystological finding concerns the generalized atherosclerosis (especially evident in coronary arteries, aorta, mesenteric arteries), and the main laboratory findings refer to mild and moderate elevation of serum cholesterol. The disease is characterised by a process of premature and accelerated aging. From theoretical and scientific standpoints, the disease is interesting as a model for studies on aging cell culture. Unfortunately, it is not yet possible to influence the outcome of the disease.