Fibromiyalji Sendromunda Enflamasyon Varliğinin Nötrofil/Lenfosit ve Platelet/Lenfosit Oranlariyla Saptanmasi Determination presence of inflammation with neutrophil/lymphocyte and platelet /lymphocyte ratios in Fibromyalgia Syndrome
2015
Objective: Our aim was to determine whether neutrophils lymphocytes and platelets lymphocytes ratios are significantly different in patients with Fibromyalgia Syndrome compared to the patients with healthy people. In this way, we want to obtain a view of the presence of inflammation in FMS even if subclinical inflammation. Methods: FMS patients were followed up at the outpatient Physical Therapy of Abant Izzet Baysal University were examined retrospectively from the records. We elaborated blood count, glucose, liver and kidney enzymes, thyroid and parathyroid hormone levels, iron, iron binding capacity, folate, ferritin, serum lipid levels, vitamin B12 and D, sedimentation, CRP, RF and Brucella test in all patients. We received the people as the control group were found to be healthy by looking at blood counts and had no complaints. Results: A total of 120 people, 80 patients and 40 healthy people without any disorder admitted to Physical Therapy Outpatient Clinic, was randomly included in the study. Glucose, liver and kidney enzyme levels, triglycerides, cholesterol, LDL, HDL, VLDL, TSH, PTH, sedimentation, CRP, RF values are within normal limits in the patients, these had no signs of infection. There was no statistically significant difference between values of N/L and P/L ratios in the patient and control group. 47 patients had low levels of vitamin D. Conclusion: Our results reported that N/L and P/L ratios, alleged to be able used as an inflammatory marker were not significantly different in patients with FMS compared to the control group. This result shows us there is no inflammation in pathogenesis of FMS even if subclinical inflammation and it is meaningless to compare severity of symptoms with these rates.
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