Purification method of hyaluronic acid or salt thereof
2002
The present invention relates to a hyaluronic acid salt, and a method of purification. In particular, the invention relates to a purification method which comprises a method for purifying a hyaluronic acid or a salt thereof from the culture broth of a hyaluronic acid-producing strain, was added to the aromatic adsorbing resin to the culture of hyaluronic acid-producing strain adsorbed impurities and remove them, to remove pyrogenic substances, proteins, nucleic acids and metallic impurities with the present invention a highly efficient, and can be repeated several times to prepare a high purity hyaluronic acid in a simple and cheap purification process by minimizing the number of times that the organic solvent precipitation. Hyaluronic acid, purified, aromatic adsorbing resin
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