Quantitative Analysis of Computed Tomography Scans of the Lungs for the Diagnosis of Pulmonary Emphysema: A Validation Study of a Semiautomated Contour Detection Technique

RATIONALE AND OBJECTIVES.To develop an analytic software package based on automated contour detection for the objective and reproducible assessment of emphysema from computed tomography (CT) scans.METHODS.A semiautomated technique was developed for the definition of lung contours in CT cross-section