Preparation of sustained release tablets and diclofenac sodium

The invention relates to the technical field of medicine, in particular to diclofenac sodium sustained release tablets and a preparation process thereof. The diclofenac sodium sustained release tablets provided by the invention comprise the following components in percentage by mass: 16.5 to 39.0 percent of diclofenac sodium, 10.0 to 35.5 percent of sustained release agent, 33.5 to 65.0 percent of filling agent, 2.01 to 8.0 percent of glidant, 0 to 2.5 percent of lubricating agent, and 0 to 8.0 percent of adhesive. According to the diclofenac sodium sustained release tablets and a whole-powder direct tabletting method thereof provided by the invention, by changing the components and the preparation method, the production process is simplified, the production cost is reduced, the production efficiency is improved, the yield is improved to 98.0 to 100 percent, granule condensation is avoided, the surface of the tablets is smooth, meanwhile, consumption of high-concentration alcohol is avoided, and the potential safety hazard in the production process is reduced.