Obesity and female androgenic alopecia: A cause and an effect?

In this patient the clinical, histologic, and immunopathologic features werecompatible with the diagnosis of BP.2BothDIF and IIF on salt-split skin substrate revealed anti-BMZantibodies, whichfulfilled themajordiagnostic criteriaforBP.3The main question iswhether the BP wasactuallyinduced by the preceding burns or whether it appearedcoincidentally. We believe the first possibility is more likely becausethe disease wastransientand did not recur for a long period, even withouttherapy. Circulating BP or pemphigus antibodies may occur at lowtiters in the serumof patientswith burn weeks after injury, althoughimmunohistochemical studies of patients' skin havefailed to detectany anti-BMZ antibodyactivity inthesecases." However, Chorzelski et a1.5 observed onepatient with burn-provoked BP in a series of ninepatients with induced BP. Recently Jevtic and Grigoris'' described a case of BP that originatedin a burn site. Pemphigus, another autoimmune blistering disease, has also been reported to occur after a burn." Journal of the American Academy of Dermatology June 1994