A REVIEW ON ORAL THIN FAST DISSOLVING FILMS RECENT TREND OF DOSAGE FORM FOR QUICK RELEASE

The oral route is most popular route for the administration of therapeutic agents because of low cost of therapy and ease of administration lead to high levels of patient compliance. In the recent years, many of the pharmaceutical groups are focusing their research on rapid dissolving technology.The main advantage of this technology is the administration to pediatric and geriatric patient population where the difficulty of swallowing larger oral dosage forms is eliminated orally. Fast dissolving film is the type of drug delivery system which, when placed in the oral cavity, disintegrate or dissolve within few seconds without the intake of water.New taste-masking agents allow bitter ingredients to be successfully formulated.Oral thin fast dissolving films (OTFDFs) can be formulated b y r e d u c e d d o s a g e f r e q u e n c y with selected oral cavity absorption enhancers in a suitable oral cavity film carrier.This facilitates the rapid absorption in the oral cavity for drugs with low GIT-bioavailability and intensive first-pass effects. Thus, it offers shortening onset time, enhancing bioavailability and reducing the probability of first pass side effect. In the present review, an account of various formulation considerations, methods of preparations, different technologies, evaluation as well as packaging and application is compiled.