Platelet activation suppresses HIV-1 infection of T cells

Theodros Solomon Tsegaye,Kerstin Gnirß,Niels Rahe-Meyer,Miriam Kiene,Annika Krämer-Kühl,Georg M. N. Behrens,Jan Münch,Stefan Pöhlmann

Platelet activation suppresses HIV-1 infection of T cells

2013

Theodros Solomon Tsegaye
Kerstin Gnirß
Niels Rahe-Meyer
Miriam Kiene
Annika Krämer-Kühl
Georg M. N. Behrens
Jan Münch
Stefan Pöhlmann

Background Platelets, anucleate cell fragments abundant in human blood, can capture HIV-1 and platelet counts have been associated with viral load and disease progression. However, the impact of platelets on HIV-1 infection of T cells is unclear.

Keywords:

Platelet factor 4
Immunology
Virology
Cell
Disease
Platelet
Biology
Viral load
human blood
human immunodeficiency virus
platelet activation
Antibody

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