Pomegranate rind and novel method for improving prostate gland symptoms with carthaginian apple seed extract

2008 
The invention provides an extract from the peel and the seeds of Punica granatum. The extract can be used for preparing drugs as well as health food and food additives for treating hyperplasia of prostate and prostatitis. Experimental results on mice with hyperplasia of prostate show that the extract from the peel and the seeds of Punica granatum can effectively improve the prostate weight and prostate index, improve malondialdehyde (MDA) level and testosterone level in prostate, improve antioxidant ability in plasma, and regulate nitrogen oxide (NO) level in plasma. Also, the experimental results show that the extract from the peel and the seed of Punica granatum can improve the lecithin corpuscle density and leukocyte count in prostate, increase the activity of prostatic acid phosphatase (PACP), and regulate the MDA and NO levels in prostate. The in vitro experiments show that the extract from the peel and the seeds of Punica granatum has strong antioxidant effect. The extract from the peel and the seeds of Punica granatum has high safety and definite bioactivity. Therefore, the dose of the extract from peel and seed of Punica granatum in finished products of drugs, health food or food additives is 0.001-100 wt%.
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