Crystalline Phase Differentiation in Urinary Calcium Phosphate and Magnesium Phosphate Calculi

Phosphates are encountered as the main components in about 15% of urinary calculi. Except for struvite, no specific correlations have been found between the crystalline phase of the phosphates and the cause of nephrolithiasis. Objective: The relationship between aetiological factors and crystalline phases or carbonate rate in calcium phosphate stones were assessed. Material and Methods: From a series of 1148 phosphate calculi, we investigated the relationship between composition and aetiological factors. Results: Carbapatite was the most frequent crystalline phase (74.0%). It was associated with many possible causes, including hypercalciuria, hypocitraturia, primary hyperparathyroidism, tubular acidosis, medullary sponge kidney and chronic urinary tract infection. The carbonate rate of carbapatite may be of clinical interest because carbonate rates above 15% are frequently related to urinary tract infection with urea-splitting bacteria. Conversely, the carbonate rate was commonly less than 10% in cases of...