УТОЛЩЕНИЕ КОМПЛЕКСА “ИНТИМАQМЕДИА” И АССОЦИИРОВАННЫЕ С НИМ ФАКТОРЫ У ВЗРОСЛОГО ГОРОДСКОГО НАСЕЛЕНИЯ

The objective of the scientific work was to study the prevalence of increased carotid intima media thickness (cIMT) in the general  employable population of Tomsk and to determine cardiovascular risk  factors, explaining its variation to the greatest extent. With the  currently recommended criteria and measuring technique, there was  established, that the prevalence of increased cIMT in the population  did not exceed 10%, showed quite rare occurrence among the  individuals younger than 50 years old, whereas in the older ones it  was characterized by the further increase with age, emerging in the  every forth man and the every seventh woman. Beyond the age,  variation of the prevalence in the population was explained by such  risk factors as obesity, pulse blood pressure (BP), high density  lipoproteins (HDL), regular smoking, and the role of the factors was not the same between men and women. The leading associative factor in men was obesity, whereas in women the independent  associations were found with respect to pulse BP and HDL. In men  with HDL levels below 0.95 mmol/l the effect of obesity was  significantly higher in magnitude than the average effect in men. The  association of pulse BP in women showed stepwise decrease in  its magnitude as the age increased. The independent role of regular  smoking was not so prominent and showed a limited significance only. Our main findings confirm some reproducible tendencies, demonstrated by the modern epidemiologic data, and  evidence that in the employable population increased cIMT is prevalent only starting up with the sixth decade of life and the  probability of its occurrence is mainly influenced by the major  cardiovascular metabolic risk factors – obesity, HDL, as well as  systolic and pulse BP.