Mucous membrane pemphigoid with severe stricture of the esophagus mediated by IgG and IgA autoantibodies to LAD-1

Stricture of the esophagus may develop in the course of different blistering disorders, mainly mucous membrane pemphigoid (MMP) [1]. MMP is characterized by the presence of IgG and/or IgA autoantibodies directed to the basement membrane zone (BMZ) [1]. We report the first case of MMP with severe stricture of the esophagus mediated by both IgG and IgA autoantibodies directed exclusively to LAD-1, which is a target antigen in linear IgA bullous dermatosis (LABD). A 78-year-old woman was admitted to [...]