Intralesional curettage versus prosthetic replacement, which approach is suitable for GCT?——— A finite element biomechanics analysis of limb-salvage simulation

Abstract Background To compare mechanical properties of femoral tumor treatments to optimize operative strategies for limb tumor surgery of Giant Cell Tumor (GCT). Methods: Fourteen femoral CT images with GCT were randomly selected to rebuild 3D models by MIMICS. They were then executed by reverse engineering software for simulative modes: Mode #1: Intralesional curettage with cement-filled plus fixator and Mode #2: Distal femur resection with tumorous prosthesis replaced. Finally, the mechanical aspects, such as stress and displacement, were compared by finite element analysis. Results Analyzed by AnSys, the observation indexes were measured as follows: for displacement of femurs, d = 1.4762 ( Conclusions Our finite element biomechanics analysis of limb-salvage simulation proved that to treat distal femoral bone GCT, prosthetic replacement is more efficient than intralesional curettage.