Evaluation Of Serum Uric Acid, Serum CRP With Microalbuminuria In Type 2DM.

Diabetes mellitus is a major emerging clinical health problem in the 21 st centuary. Diabetic nephropathy is one of the most common consequences of diabetes mellitus. Evidence shows that subclinical chronic inflammation is involved in the pathogenesis of diabetic nephropathy. To determine the significant association between serum CRP, serum uric acid and microalbuminuria in type 2 diabetic patients. This is cross sectional study carried out in 100 diagnosed type 2 diabetic patients. Blood sample collected for the analysis of serum CRP, serum uric acid, HbA1c, and early morning mid-stream urine sample for the estimation of the microalbuminuria. Data was statistically analysed. Serum uric acid and serum CRP shows significant association with microalbuminuria in type 2 diabetic patients. Elevated serum CRP and serum uricacid level were associated with microalbuminuria in type 2 diabetic patients suggesting the risk factors for the development of incipient diabetic nephropathy. Thus regular screening of serum CRP and serum uric acid along with microalbuminuria helpful in risk prediction of diabetic nephropathy and early intervention to prevent complications.