Peters' anomaly and systemic defects.

To the Editor. —With great interest, we read the article of Kivlin et al 1 on a new syndrome, consisting of Peters' anomaly and short-limbed dwarfism. This prompted us to point to the publication in 1984 in which we described 11 patients with similar clinical features and called this entity Peters'-Plus syndrome. 2 In addition to Peters' anomaly, we considered four signs of importance for this entity—short stature, cleft lip and/or palate, mental retardation, and brachymorphism. However, four of our 11 patients lacked palatoschisis. Like Kivlin et al, we supposed that an autosomal recessive inheritance had occurred because there were two sibling-pairs among our patients. As the mental handicap can be very serious, it is important to diagnose this syndrome and to give appropriate genetic advice to the parents of an affected child.