A new domain in the Toll/IL-1R domain-containing adaptor inducing interferon-β factor protein amino terminus is important for tumor necrosis factor-α receptor-associated factor 3 association, protein stabilization and interferon signaling.

Vinh Phuc Nguyen,Jing Chen,Michael N. Petrus,Carolyn K. Goldman,Michael J. Kruhlak,Richard Bamford,Thomas A. Waldmann

A new domain in the Toll/IL-1R domain-containing adaptor inducing interferon-β factor protein amino terminus is important for tumor necrosis factor-α receptor-associated factor 3 association, protein stabilization and interferon signaling.

2014

Vinh Phuc Nguyen
Jing Chen
Michael N. Petrus
Carolyn K. Goldman
Michael J. Kruhlak
Richard Bamford
Thomas A. Waldmann

Toll/IL-1R domain-containing adaptor inducing interferon-s (IFN-s) factor (TRIF) is a key adaptor for Toll-like receptor (TLR) 3 and TLR4 signaling. Using a novel cDNA isolate encoding a TRIF protein

Keywords:

Immunology
Virology
TLR4
Tumor necrosis factor alpha
Transport protein
Interferon
TRIF
Signal transduction
TNF Receptor-Associated Factor 3
Molecular biology
Biology
NFKB1
Receptor
protein stabilization

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