Roles of dendritic cell in disease progression of AIDS primate models
2010
Non-human primate models are widely used in research of AIDS mechanism,
transmission, vaccine and drugs. Dendritic cells (DC), as antigen
presenting cells linking the innate immunity and acquired immunity,
play a pivotal role in AIDS progression. Studies on the change of DC
subsets number, phenotype and function in AIDS non-human primate models
are important for revealing some mechanism of AIDS progression. This
article reviews the progress in DC subsets of non-human primate AIDS
models, which will provide an avenue for further study in AIDS.
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