Synthesis of New Imidazo[4,5-e][1,3]thiazolo-[3,2-b][1,2,4]triazine Derivatives

Previously unknown (Z)-6-aryl(hetaryl)methylidene derivatives of imidazo[4,5-e][1,3]thiazolo[3,2-b]-[1,2,4]triazine-2,7-diones were synthesized by aldol-crotonic condensation of imidazo[4,5-e]-[1,3]thiazolo[3,2-b][1,2,4]triazine-2,7-diones with aromatic or heteroaromatic aldehydes, or by three-component condensation of imidazo[4,5-e][1,2,4]triazine-3-thione, bromoacetic acid, and aldehyde.