Effects of FIO2 on leg ˙VO2 during cycle ergometry in sedentary subjects

ABSTRACTIn a recent study of completely sedentary normal young subjects, leg˙VO2max was reduced by hypoxia in proportion to mean capillary PO2 as FIO2 was reduced from 0.15 to 0.12. However, the increase in ˙VO2max from FIO2 = 0.15 to 0.21 was less than expected for the increase in mean capillary PO