The study of osteoblast adhesion on pure titanium implant surface modified by microarc oxidation:An in vitro study

PURPOSE:To study the biocompatibility of osteoblasts on pure titanium surface modified by microarc oxidation.METHODS:Microarc oxidation was performed on titanium in an electrolyte containing disodium hydrogen phosphate calcium and calcium acetate using a direct current power supply.The micrograph was observed by scanning electron microscope,the surface structure was analyzed by X-ray diffraction and the composition of the surface was detected by EDS.Cell adhesion was studied by cultivating osteoblast on differently treated titanium surfaces.The result was processed by SPSS 11.0 software package for one-way ANOVA.RESULTS:The ceramic films displayed a porous and rough structure on pure titanium surface.The ceramic thin films on titanium surface modified by MAO exhibited better cell adhesion to osteoblast than that of pure titanium,and anodic oxidation titanium(P0.05).CONCLUSION:It was found that MAO is a suitable method forming a ceramic thin film containing Ca2+ and P3-on the titanium surface.The technique improves the cytocompatibility of titanium implants,and the film is indicable for osteoblast proliferation and subsequent bone formation.Supported by Key Science and Technology Project of Hubei Province(Grant No.4-260).